The Role of Oncogenes and Tumor Suppressors in Cancer Development

This examination focuses on the functions of oncogenes and tumor suppressor genes in the regulation of cell growth and proliferation. Candidates are expected to understand the molecular basis for how alterations in these genes contribute to cancer development.

An understanding of these genetic elements is crucial for deciphering the pathways leading to malignant transformation. Furthermore, knowledge of oncogenes and tumor suppressors is integral for targeted therapies aimed at specific molecular targets in cancer treatment.

Candidates will be assessed on their ability to explain the mechanisms by which mutations in oncogenes and tumor suppressor genes drive cancer. This includes discussing examples of specific genes and the consequences of their dysregulation.

Discussion may also extend to the implications of these alterations in cancer diagnostics, prognostics, and therapeutic interventions, highlighting the translational aspects of cancer biology.